产品名称
GATA-6 Rabbit Polyclonal Antibody
别名
GATA6; Transcription factor GATA-6; GATA-binding factor 6
蛋白名称
Transcription factor GATA-6
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2627
Human Swissprot No.
Q92908
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q92908/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=14465
Mouse Swissprot No.
Q61169
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q61169
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29300
Rat Swissprot Link
http://www.uniprot.org/uniprot/P46153
免疫原
The antiserum was produced against synthesized peptide derived from human GATA6. AA range:461-510
特异性
GATA-6 Polyclonal Antibody detects endogenous levels of GATA-6 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene is a member of a small family of zinc finger transcription factors that play an important role in the regulation of cellular differentiation and organogenesis during vertebrate development. This gene is expressed during early embryogenesis and localizes to endo- and mesodermally derived cells during later embryogenesis and thereby plays an important role in gut, lung, and heart development. Mutations in this gene are associated with several congenital defects. [provided by RefSeq, Mar 2012],
组织表达
Expressed in heart, gut and gut-derived tissues. Expressed in skin upper pilosebaceous unit. Expression is decreased or lost in acne lesions (PubMed:33082341).
功能
function:Thought to be important for regulating terminal differentiation and/or proliferation.,similarity:Contains 2 GATA-type zinc fingers.,tissue specificity:Expressed in heart, gut and gut-derived tissues.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
