产品名称
GATA-5 Rabbit Polyclonal Antibody
别名
GATA5; Transcription factor GATA-5; GATA-binding factor 5
蛋白名称
Transcription factor GATA-5
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=140628
Human Swissprot No.
Q9BWX5
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9BWX5/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=14464
Mouse Swissprot No.
P97489
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P97489
免疫原
The antiserum was produced against synthesized peptide derived from human GATA-5. AA range:244-293
特异性
GATA-5 Polyclonal Antibody detects endogenous levels of GATA-5 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a transcription factor that contains two GATA-type zinc fingers. The encoded protein is known to bind to hepatocyte nuclear factor-1alpha (HNF-1alpha), and this interaction is essential for cooperative activation of the intestinal lactase-phlorizin hydrolase promoter. In other organisms, similar proteins may be involved in the establishment of cardiac smooth muscle cell diversity. [provided by RefSeq, Jul 2008],
功能
function:Binds to the functionally important CEF-1 nuclear protein binding site in the cardiac-specific slow/cardiac troponin C transcriptional enhancer. May play an important role in the transcriptional program(s) that underlies smooth muscle cell diversity.,similarity:Contains 2 GATA-type zinc fingers.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
