产品名称
Galectin-7 Rabbit Polyclonal Antibody
别名
LGALS7; PIG1; LGALS7B; Galectin-7; Gal-7; HKL-14; PI7; p53-induced gene 1 protein
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
3963/653499
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3963
Human Swissprot No.
P47929
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P47929/entry
Mouse Swissprot No.
O54974
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O54974
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29518
Rat Swissprot Link
http://www.uniprot.org/uniprot/P97590
免疫原
The antiserum was produced against synthesized peptide derived from human LEG7. AA range:41-90
特异性
Galectin-7 Polyclonal Antibody detects endogenous levels of Galectin-7 protein.
稀释度
WB 1:500-2000 IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridization studies indicate that this lectin is specifically expressed in keratinocytes and found mainly in stratified squamous epithelium. A duplicate copy of this gene (GeneID:653499) is found adjacent to, but on the opposite strand on chromosome 19. [provided by RefSeq, Jul 2008],
组织表达
Mainly expressed in stratified squamous epithelium.
细胞定位
Cytoplasm . Nucleus . Secreted . May be secreted by a non-classical secretory pathway.
功能
function:Could be involved in cell-cell and/or cell-matrix interactions necessary for normal growth control. Pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release.,induction:By p53.,online information:Galectin-7,similarity:Contains 1 galectin domain.,subcellular location:May be secreted by a non-classical secretory pathway.,subunit:Monomer.,tissue specificity:Mainly in stratified squamous epithelium.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
