产品名称
GABA T-3 Rabbit Polyclonal Antibody
别名
SLC6A11; GABT3; GAT3; Sodium- and chloride-dependent GABA transporter 3; GAT-3; Solute carrier family 6 member 11
蛋白名称
Sodium- and chloride-dependent GABA transporter 3
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6538
Human Swissprot No.
P48066
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P48066/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=243616
Mouse Swissprot No.
P31650
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P31650
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=79213
Rat Swissprot Link
http://www.uniprot.org/uniprot/P31647
免疫原
Synthesized peptide derived from GABA T-3 . at AA range: 370-450
特异性
GABA T-3 Polyclonal Antibody detects endogenous levels of GABA T-3 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a sodium-dependent transporter that uptakes gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, which ends the GABA neurotransmission. Defects in this gene may result in epilepsy, behavioral problems, or intellectual problems. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015],
组织表达
Widespread distribution in the brain.
细胞定位
Membrane; Multi-pass membrane protein.
功能
function:Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals.,similarity:Belongs to the sodium:neurotransmitter symporter (SNF) family.,tissue specificity:Widespread distribution in the brain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
