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FXR2 Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT1803
产品名称
FXR2 Rabbit Polyclonal Antibody
别名
FXR2; FMR1L2; Fragile X mental retardation syndrome-related protein 2
类别
常规抗体
基因名称
FXR2
蛋白名称
Fragile X mental retardation syndrome-related protein 2
推荐应用
WB
反应种属
Human,Mouse
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
9513
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9513
Human Swissprot No.
P51116
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P51116/entry
Mouse Swissprot No.
Q9WVR4
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9WVR4
免疫原
The antiserum was produced against synthesized peptide derived from human FXR2. AA range:551-600
特异性
FXR2 Polyclonal Antibody detects endogenous levels of FXR2 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
预测分子量
74kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. This encoded protein may self-associate or interact with FMRP and FXR1. It may have a role in the development of fragile X mental retardation syndrome. [provided by RefSeq, Jul 2008],
组织表达
Brain,Epithelium,Lymph,PNS,Skin,
细胞定位
Cytoplasm.
功能
function:RNA-binding protein.,similarity:Belongs to the FMR1 family.,similarity:Contains 2 KH domains.,subunit:Interacts with FMR1 and FXR1. Interacts with CYFIP2 but not with CYFIP1. Interacts with TDRD3.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunofluorescence analysis of A549 cells, using FXR2 Antibody. The picture on the right is blocked with the synthesized peptide.

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using FXR2 Antibody. The picture on the right is blocked with the synthesized peptide.

Western blot analysis of lysates from COLO205 cells, using FXR2 Antibody. The lane on the right is blocked with the synthesized peptide.

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