产品名称
Fucokinase Rabbit Polyclonal Antibody
别名
FUK; L-fucose kinase; Fucokinase
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=197258
Human Swissprot No.
Q8N0W3
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q8N0W3/entry
免疫原
The antiserum was produced against synthesized peptide derived from human FUK. AA range:11-60
特异性
Fucokinase Polyclonal Antibody detects endogenous levels of Fucokinase protein.
稀释度
WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
fucokinase(FUK) Homo sapiens The protein encoded by this gene belongs to the GHMP (galacto-, homoserine, mevalonate and phosphomevalonate) kinase family and catalyzes the phosphorylation of L-fucose to form beta-L-fucose 1-phosphate. This enzyme catalyzes the first step in the utilization of free L-fucose in glycoprotein and glycolipid synthesis. L-fucose may be important in mediating a number of cell-cell interactions such as blood group antigen recognition, inflammation, and metastatis. While several transcript variants may exist for this gene, the full-length nature of only one has been described to date. [provided by RefSeq, Jul 2008],
组织表达
Expressed in fibroblasts.
信号通路
Fructose and mannose metabolism;Amino sugar and nucleotide sugar metabolism;
功能
catalytic activity:ATP + L-fucose = ADP + beta-L-fucose 1-phosphate.,function:Takes part in the salvage pathway for reutilization of fucose from the degradation of oligosaccharides.,similarity:Belongs to the GHMP kinase family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
