产品名称
FTβ Rabbit Polyclonal Antibody
别名
FNTB; Protein farnesyltransferase subunit beta; FTase-beta; CAAX farnesyltransferase subunit beta; Ras proteins prenyltransferase subunit beta
蛋白名称
Protein farnesyltransferase subunit beta
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2342
Human Swissprot No.
P49356
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P49356/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=110606
Mouse Swissprot No.
Q8K2I1
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8K2I1
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=64511
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q02293
免疫原
The antiserum was produced against synthesized peptide derived from human FNTB. AA range:255-304
特异性
FTβ Polyclonal Antibody detects endogenous levels of FTβ protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
catalytic activity:Farnesyl diphosphate + protein-cysteine = S-farnesyl protein + diphosphate.,cofactor:Binds 1 zinc ion per subunit.,function:Catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.,similarity:Belongs to the protein prenyltransferase subunit beta family.,similarity:Contains 5 PFTB repeats.,subunit:Heterodimer of an alpha and a beta subunit.,
组织表达
Neuroblastoma,Placenta,Retina,
细胞定位
cytosol,microtubule associated complex,protein farnesyltransferase complex,
功能
catalytic activity:Farnesyl diphosphate + protein-cysteine = S-farnesyl protein + diphosphate.,cofactor:Binds 1 zinc ion per subunit.,function:Catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.,similarity:Belongs to the protein prenyltransferase subunit beta family.,similarity:Contains 5 PFTB repeats.,subunit:Heterodimer of an alpha and a beta subunit.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
