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Fra-1 Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT1772
产品名称
Fra-1 Rabbit Polyclonal Antibody
别名
FOSL1; FRA1; Fos-related antigen 1; FRA-1
类别
常规抗体
基因名称
FOSL1
蛋白名称
Fos-related antigen 1
推荐应用
WB
反应种属
Human,Mouse,Rat
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
8061
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8061
Human Swissprot No.
P15407
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P15407/entry
Mouse Gene ID
14283
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=14283
Mouse Swissprot No.
P48755
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P48755
Rat Gene ID
25445
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25445
Rat Swissprot No.
P10158
Rat Swissprot Link
http://www.uniprot.org/uniprot/P10158
免疫原
The antiserum was produced against synthesized peptide derived from human Fra-1. AA range:101-150
特异性
Fra-1 Polyclonal Antibody detects endogenous levels of Fra-1 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
预测分子量
43kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014],
组织表达
Blood,Endothelial cell,Kidney,Skin,
细胞定位
Nucleus .
信号通路
WNT;WNT-T CELL
功能
similarity:Belongs to the bZIP family.,similarity:Belongs to the bZIP family. Fos subfamily.,similarity:Contains 1 bZIP domain.,subunit:Heterodimer.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western blot analysis of lysates from HT-29 cells, using Fra-1 Antibody. The lane on the right is blocked with the synthesized peptide.

Western Blot analysis of various cells using Fra-1 Polyclonal Antibody diluted at 1:2000

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