产品名称
FoxJ1 Rabbit Polyclonal Antibody
别名
FOXJ1; FKHL13; HFH4; Forkhead box protein J1; Forkhead-related protein FKHL13; Hepatocyte nuclear factor 3 forkhead homolog 4; HFH-4
蛋白名称
Forkhead box protein J1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2302
Human Swissprot No.
Q92949
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q92949/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=15223
Mouse Swissprot No.
Q61660
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q61660
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=116557
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q63247
免疫原
The antiserum was produced against synthesized peptide derived from human FOXJ1. AA range:271-320
特异性
FoxJ1 Polyclonal Antibody detects endogenous levels of FoxJ1 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the forkhead family of transcription factors. Similar genes in zebrafish and mouse have been shown to regulate the transcription of genes that control the production of motile cilia. The mouse ortholog also functions in the determination of left-right asymmetry. Polymorphisms in this gene are associated with systemic lupus erythematosus and allergic rhinitis.[provided by RefSeq, Sep 2009],
组织表达
Testis, oviduct, lung and brain cortex.
功能
developmental stage:Expressed in developing lung, kidney and central nervous system.,disease:Genetic variations in FOXJ1 may be associated with susceptibility to allergic rhinitis (ALRH) [MIM:607154]. Allergic rhinitis is a common disease of complex inheritance and is characterized by mucosal inflammation caused by allergen exposure.,function:May play an important role in cell fate determination during lung development and in spermatogenesis.,similarity:Contains 1 fork-head DNA-binding domain.,tissue specificity:Testis, oviduct, lung and brain cortex.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
