产品名称
FMIP Rabbit Polyclonal Antibody
别名
THOC5; C22orf19; KIAA0983; THO complex subunit 5 homolog; Functional spliceosome-associated protein 79; fSAP79; NF2/meningioma region protein pK1.3; Placental protein 39.2; PP39.2; hTREX90
蛋白名称
THO complex subunit 5 homolog
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8563
Human Swissprot No.
Q13769
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q13769/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=107829
Mouse Swissprot No.
Q8BKT7
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BKT7
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=360972
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q68FX7
免疫原
The antiserum was produced against synthesized peptide derived from human THOC5. AA range:561-610
特异性
FMIP Polyclonal Antibody detects endogenous levels of FMIP protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:May be involved in the differentiation of granulocytes and adipocytes.,PTM:Phosphorylated on tyrosine upon binding to activated CSF1R; which causes a dissociation of the two proteins. Phosphorylation on Ser-5 and/or Ser-6 is required for nuclear export. Phosphorylated on Thr-328 in insulin-stimulated adipocytes (By similarity). Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the THOC5 family.,subcellular location:Shuttles between nucleus and cytoplasm.,subunit:Interacts with phosphorylated CSF1R.,tissue specificity:Ubiquitously expressed.,
组织表达
Ubiquitously expressed.
细胞定位
Nucleus . Cytoplasm . Shuttles between nucleus and cytoplasm. .
功能
function:May be involved in the differentiation of granulocytes and adipocytes.,PTM:Phosphorylated on tyrosine upon binding to activated CSF1R; which causes a dissociation of the two proteins. Phosphorylation on Ser-5 and/or Ser-6 is required for nuclear export. Phosphorylated on Thr-328 in insulin-stimulated adipocytes (By similarity). Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the THOC5 family.,subcellular location:Shuttles between nucleus and cytoplasm.,subunit:Interacts with phosphorylated CSF1R.,tissue specificity:Ubiquitously expressed.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
