产品名称
Fibulin-2 Rabbit Polyclonal Antibody
别名
FBLN2; Fibulin-2; FIBL-2
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2199
Human Swissprot No.
P98095
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P98095/entry
Mouse Swissprot No.
P37889
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P37889
免疫原
The antiserum was produced against synthesized peptide derived from human FBLN2. AA range:241-290
特异性
Fibulin-2 Polyclonal Antibody detects endogenous levels of Fibulin-2 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes an extracellular matrix protein, which belongs to the fibulin family. This protein binds various extracellular ligands and calcium. It may play a role during organ development, in particular, during the differentiation of heart, skeletal and neuronal structures. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
组织表达
Component of both basement membranes and other connective tissues. Expressed in heart, placenta and ovary.
细胞定位
Secreted, extracellular space, extracellular matrix.
功能
developmental stage:Widely expressed during embryonic development. Primarily detected within the neuropithelium, spinal ganglia and peripheral nerves.,function:Its binding to fibronectin and some other ligands is calcium dependent.,similarity:Belongs to the fibulin family.,similarity:Contains 11 EGF-like domains.,similarity:Contains 3 anaphylatoxin-like domains.,subunit:Homotrimer; disulfide-linked. Interacts with LAMA2.,tissue specificity:Component of both basement membranes and other connective tissues. Expressed in heart, placenta and ovary.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
