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FGF-22 Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT1698
产品名称
FGF-22 Rabbit Polyclonal Antibody
别名
FGF22; Fibroblast growth factor 22; FGF-22
类别
常规抗体
基因名称
FGF22
蛋白名称
Fibroblast growth factor 22
推荐应用
WB
反应种属
Human,Mouse,Rat
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
27006
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=27006
Human Swissprot No.
Q9HCT0
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9HCT0/entry
Mouse Gene ID
67112
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=67112
Mouse Swissprot No.
Q9ESS2
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9ESS2
免疫原
The antiserum was produced against synthesized peptide derived from human FGF22. AA range:71-120
特异性
FGF-22 Polyclonal Antibody detects endogenous levels of FGF-22 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
预测分子量
20kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The mouse homolog of this gene was found to be preferentially expressed in the inner root sheath of the hair follicle, which suggested a role in hair development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],
组织表达
Placenta,
细胞定位
Secreted .
信号通路
MAPK_ERK_Growth;MAPK_G_Protein;Regulates Actin and Cytoskeleton;Pathways in cancer;Melanoma;
功能
function:May be involved in hair development.,similarity:Belongs to the heparin-binding growth factors family.,subunit:Interacts with FGFBP1.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunofluorescence analysis of MCF7 cells, using FGF22 Antibody. The picture on the right is blocked with the synthesized peptide.

Immunohistochemistry analysis of paraffin-embedded human ovary tissue, using FGF22 Antibody. The picture on the right is blocked with the synthesized peptide.

Western blot analysis of lysates from Jurkat and HT-29 cells, using FGF22 Antibody. The lane on the right is blocked with the synthesized peptide.

Western Blot analysis of various cells using FGF-22 Polyclonal Antibody diluted at 1:1000

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