产品名称
FGF-22 Rabbit Polyclonal Antibody
别名
FGF22; Fibroblast growth factor 22; FGF-22
蛋白名称
Fibroblast growth factor 22
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=27006
Human Swissprot No.
Q9HCT0
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9HCT0/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=67112
Mouse Swissprot No.
Q9ESS2
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9ESS2
免疫原
The antiserum was produced against synthesized peptide derived from human FGF22. AA range:71-120
特异性
FGF-22 Polyclonal Antibody detects endogenous levels of FGF-22 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The mouse homolog of this gene was found to be preferentially expressed in the inner root sheath of the hair follicle, which suggested a role in hair development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],
信号通路
MAPK_ERK_Growth;MAPK_G_Protein;Regulates Actin and Cytoskeleton;Pathways in cancer;Melanoma;
功能
function:May be involved in hair development.,similarity:Belongs to the heparin-binding growth factors family.,subunit:Interacts with FGFBP1.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.