产品名称
Fibulin-2 Rabbit Polyclonal Antibody
别名
FBLN2; Fibulin-2; FIBL-2
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2199
Human Swissprot No.
P98095
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P98095/entry
Mouse Swissprot No.
P37889
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P37889
免疫原
The antiserum was produced against synthesized peptide derived from human FBLN2. AA range:241-290
特异性
Fibulin-2 Polyclonal Antibody detects endogenous levels of Fibulin-2 protein.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes an extracellular matrix protein, which belongs to the fibulin family. This protein binds various extracellular ligands and calcium. It may play a role during organ development, in particular, during the differentiation of heart, skeletal and neuronal structures. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
组织表达
Component of both basement membranes and other connective tissues. Expressed in heart, placenta and ovary.
细胞定位
Secreted, extracellular space, extracellular matrix.
功能
developmental stage:Widely expressed during embryonic development. Primarily detected within the neuropithelium, spinal ganglia and peripheral nerves.,function:Its binding to fibronectin and some other ligands is calcium dependent.,similarity:Belongs to the fibulin family.,similarity:Contains 11 EGF-like domains.,similarity:Contains 3 anaphylatoxin-like domains.,subunit:Homotrimer; disulfide-linked. Interacts with LAMA2.,tissue specificity:Component of both basement membranes and other connective tissues. Expressed in heart, placenta and ovary.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
