产品名称
FASTKD3 Rabbit Polyclonal Antibody
别名
FASTKD3; FAST kinase domain-containing protein 3
蛋白名称
FAST kinase domain-containing protein 3
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=79072
Human Swissprot No.
Q14CZ7
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q14CZ7/entry
Mouse Swissprot No.
Q8BSN9
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BSN9
免疫原
The antiserum was produced against synthesized peptide derived from human FAKD3. AA range:121-170
特异性
FASTKD3 Polyclonal Antibody detects endogenous levels of FASTKD3 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of a small family of Fas-activated serine/threonine kinase domain (FASTKD) containing proteins that share an amino terminal mitochondrial targeting domain and multiple carboxy terminal FAST domains as well as a putative RNA-binding RAP domain. The members of this family are ubiquitously expressed and are generally most abundant in mitochondria-enriched tissues such as heart, skeletal muscle and brown-adipose tissue. Some members of this protein family may play a role in apoptosis. The protein encoded by this gene interacts with components of the mitochondrial respiratory and translation networks. A pseudogene of this gene is also present on chromosome 5. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013],
组织表达
Expression detected in spleen, thymus, testis, ovary, colon, heart, smooth muscle, kidney, brain, lung, liver and white adipose tissue with highest expression in liver and thyroid.
功能
similarity:Belongs to the FAST kinase family.,similarity:Contains 1 RAP domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
