产品名称
Epsin 3 Rabbit Polyclonal Antibody
别名
EPN3; Epsin-3; EPS-15-interacting protein 3
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=55040
Human Swissprot No.
Q9H201
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9H201/entry
Mouse Swissprot No.
Q91W69
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q91W69
免疫原
The antiserum was produced against synthesized peptide derived from human EPN3. AA range:401-450
特异性
Epsin 3 Polyclonal Antibody detects endogenous levels of Epsin 3 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
induction:In keratinocytes, by wounding or contact with collagen.,similarity:Belongs to the epsin family.,similarity:Contains 1 ENTH (epsin N-terminal homology) domain.,similarity:Contains 2 UIM (ubiquitin-interacting motif) repeats.,subcellular location:Concentrated in the perinuclear region and associated with clathrin-coated vesicles close to the cell periphery. May shuttle to the nucleus.,tissue specificity:Detected in migrating keratinocytes from wounded skin, but not in differentiating keratinocytes or in normal skin. Detected in chronic wounds, basal cell carcinoma and ulcerative colitis.,
组织表达
Detected in migrating keratinocytes from wounded skin, but not in differentiating keratinocytes or in normal skin. Detected in chronic wounds, basal cell carcinoma and ulcerative colitis.
细胞定位
Cytoplasm . Cytoplasm, perinuclear region . Cytoplasmic vesicle, clathrin-coated vesicle . Nucleus . Concentrated in the perinuclear region and associated with clathrin-coated vesicles close to the cell periphery. May shuttle to the nucleus.
功能
induction:In keratinocytes, by wounding or contact with collagen.,similarity:Belongs to the epsin family.,similarity:Contains 1 ENTH (epsin N-terminal homology) domain.,similarity:Contains 2 UIM (ubiquitin-interacting motif) repeats.,subcellular location:Concentrated in the perinuclear region and associated with clathrin-coated vesicles close to the cell periphery. May shuttle to the nucleus.,tissue specificity:Detected in migrating keratinocytes from wounded skin, but not in differentiating keratinocytes or in normal skin. Detected in chronic wounds, basal cell carcinoma and ulcerative colitis.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
