BD-PT1599

Eps8L2 Rabbit Polyclonal Antibody

EPS8L2; EPS8R2; PP13181; Epidermal growth factor receptor kinase substrate 8-like protein 2; EPS8-like protein 2; Epidermal growth factor receptor pathway substrate 8-related protein 2; EPS8-related protein 2

常规抗体

EPS8L2

Epidermal growth factor receptor kinase substrate 8-like protein 2

WB

Human,Mouse

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

64787

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=64787

Q9H6S3

http://www.uniprot.org/uniprotkb/Q9H6S3/entry

98845

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=98845

Q99K30

http://www.uniprot.org/uniprot/Q99K30

The antiserum was produced against synthesized peptide derived from human ES8L2. AA range:1-50

Eps8L2 Polyclonal Antibody detects endogenous levels of Eps8L2 protein.

WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

81kD

-20°C/1 year

Polyclonal, Rabbit,IgG

This gene encodes a member of the EPS8 gene family. The encoded protein, like other members of the family, is thought to link growth factor stimulation to actin organization, generating functional redundancy in the pathways that regulate actin cytoskeletal remodeling. [provided by RefSeq, Dec 2008],

Detected in fibroblasts and placenta.

Cytoplasm . Cell projection, stereocilium . Localizes at the tips of the stereocilia of the inner and outer hair cells. .

function:Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton.,similarity:Belongs to the EPS8 family.,similarity:Contains 1 PID domain.,similarity:Contains 1 SH3 domain.,subunit:Interacts with ABI1. Part of a complex that contains SOS1, ABI1 and EPS8L2. Associates with F-actin.,tissue specificity:Detected in fibroblasts and placenta.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.