产品名称
Eps8L1 Rabbit Polyclonal Antibody
别名
EPS8L1; DRC3; EPS8R1; PP10566; Epidermal growth factor receptor kinase substrate 8-like protein 1; EPS8-like protein 1; Epidermal growth factor receptor pathway substrate 8-related protein 1; EPS8-related protein 1
蛋白名称
Epidermal growth factor receptor kinase substrate 8-like protein 1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=54869
Human Swissprot No.
Q8TE68
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q8TE68/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=67425
Mouse Swissprot No.
Q8R5F8
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8R5F8
免疫原
The antiserum was produced against synthesized peptide derived from human ES8L1. AA range:411-460
特异性
Eps8L1 Polyclonal Antibody detects endogenous levels of Eps8L1 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a protein that is related to epidermal growth factor receptor pathway substrate 8 (EPS8), a substrate for the epidermal growth factor receptor. The function of this protein is unknown. At least two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
组织表达
Detected in placenta.
功能
function:Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton.,similarity:Belongs to the EPS8 family.,similarity:Contains 1 SH3 domain.,subunit:Interacts with ABI1. Part of a complex that contains SOS1, ABI1 and EPS8L2. Associates with F-actin.,tissue specificity:Detected in placenta.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
