BD-PT1589

Ephrin-A1 Rabbit Polyclonal Antibody

EFNA1; EPLG1; LERK1; TNFAIP4; Ephrin-A1; EPH-related receptor tyrosine kinase ligand 1; LERK-1; Immediate early response protein B61; Tumor necrosis factor alpha-induced protein 4; TNF alpha-induced protein 4

常规抗体

EFNA1

Ephrin-A1

WB

Human,Mouse,Rat

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

1942

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1942

P20827

http://www.uniprot.org/uniprotkb/P20827/entry

13636

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=13636

P52793

http://www.uniprot.org/uniprot/P52793

94268

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=94268

P97553

http://www.uniprot.org/uniprot/P97553

The antiserum was produced against synthesized peptide derived from human EFNA1. AA range:66-115

Ephrin-A1 Polyclonal Antibody detects endogenous levels of Ephrin-A1 protein.

WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

24kD

-20°C/1 year

Polyclonal, Rabbit,IgG

This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin which binds to the EPHA2, EPHA4, EPHA5, EPHA6, and EPHA7 receptors. Two transcript variants that encode different isoforms were identified through sequence analysis. [provided by RefSeq, Jul 2008],

Brain. Down-regulated in primary glioma tissues compared to the normal tissues. The soluble monomeric form is expressed in the glioblastoma multiforme (GBM) and breast cancer cells (at protein level).

Cell membrane ; Lipid-anchor, GPI-anchor .; [Ephrin-A1, secreted form]: Secreted .

Axon guidance;

induction:By TNF-alpha and interleukin-1 beta.,similarity:Belongs to the ephrin family.,subunit:Binds to the receptor tyrosine kinases EPHA2, EPHA4, EPHA5, EPHA6 and EPHA7. Also binds with low affinity to EPHA1.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.