产品名称
EP2 Rabbit Polyclonal Antibody
别名
PTGER2; Prostaglandin E2 receptor EP2 subtype; PGE receptor EP2 subtype; PGE2 receptor EP2 subtype; Prostanoid EP2 receptor
蛋白名称
Prostaglandin E2 receptor EP2 subtype
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5732
Human Swissprot No.
P43116
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P43116/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=19217
Mouse Swissprot No.
Q62053
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q62053
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=81752
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q62928
免疫原
The antiserum was produced against synthesized peptide derived from human PE2R2. AA range:261-310
特异性
EP2 Polyclonal Antibody detects endogenous levels of EP2 protein.
稀释度
WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a receptor for prostaglandin E2, a metabolite of arachidonic acid which has different biologic activities in a wide range of tissues. Mutations in this gene are associated with aspirin-induced susceptibility to asthma. [provided by RefSeq, Oct 2009],
细胞定位
Cell membrane; Multi-pass membrane protein.
信号通路
Neuroactive ligand-receptor interaction;
功能
function:Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Placenta and lung.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
