产品名称
EOMES Rabbit Polyclonal Antibody
别名
EOMES; TBR2; Eomesodermin homolog; T-box brain protein 2; T-brain-2; TBR-2
蛋白名称
Eomesodermin homolog
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8320
Human Swissprot No.
O95936
Human Swissprot Link
http://www.uniprot.org/uniprotkb/O95936/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=13813
Mouse Swissprot No.
O54839
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O54839
免疫原
The antiserum was produced against synthesized peptide derived from human EOMES. AA range:59-108
特异性
EOMES Polyclonal Antibody detects endogenous levels of EOMES protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene belongs to the TBR1 (T-box brain protein 1) sub-family of T-box genes that share the common DNA-binding T-box domain. The encoded protein is a transcription factor which is crucial for embryonic development of mesoderm and the central nervous system in vertebrates. The protein may also be necessary for the differentiation of effector CD8+ T cells which are involved in defense against viral infections. A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013],
组织表达
Expressed in CD8+ T-cells.
功能
similarity:Contains 1 T-box DNA-binding domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.