产品名称
EphA10 Rabbit Polyclonal Antibody
别名
EPHA10; Ephrin type-A receptor 10
蛋白名称
Ephrin type-A receptor 10
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=284656
Human Swissprot No.
Q5JZY3
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q5JZY3/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=230735
Mouse Swissprot No.
Q8BYG9
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BYG9
免疫原
The antiserum was produced against synthesized peptide derived from human EPHA10. AA range:431-480
特异性
EphA10 Polyclonal Antibody detects endogenous levels of EphA10 protein.
宿主
Polyclonal, Rabbit,IgG
背景介绍
Ephrin receptors, the largest subfamily of receptor tyrosine kinases (RTKs), and their ephrin ligands are important mediators of cell-cell communication regulating cell attachment, shape, and mobility in neuronal and epithelial cells (Aasheim et al., 2005 [PubMed 15777695]). See MIM 179610 for additional background on Eph receptors and ephrins.[supplied by OMIM, Mar 2008],
组织表达
Mainly expressed in testis.
细胞定位
[Isoform 1]: Cell membrane ; Single-pass type I membrane protein .; [Isoform 3]: Cell membrane ; Single-pass type I membrane protein .; [Isoform 2]: Secreted .
功能
catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,domain:The protein kinase domain is predicted to be catalytically inactive.,function:Receptor for members of the ephrin-A family. Binds to EFNA3, EFNA4 and EFNA5.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SAM (sterile alpha motif) domain.,similarity:Contains 2 fibronectin type-III domains.,tissue specificity:Mainly expressed in testis.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
