产品名称
EMR1 Rabbit Polyclonal Antibody
别名
EMR1; TM7LN3; EGF-like module-containing mucin-like hormone receptor-like 1; EGF-like module receptor 1; EMR1 hormone receptor
蛋白名称
EGF-like module-containing mucin-like hormone receptor-like 1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2015
Human Swissprot No.
Q14246
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q14246/entry
Mouse Swissprot No.
Q61549
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q61549
免疫原
The antiserum was produced against synthesized peptide derived from human EMR1. AA range:818-867
特异性
EMR1 Polyclonal Antibody detects endogenous levels of EMR1 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a protein that has a domain resembling seven transmembrane G protein-coupled hormone receptors (7TM receptors) at its C-terminus. The N-terminus of the encoded protein has six EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012],
组织表达
Expression is restricted to eosinophils.
细胞定位
Cell membrane ; Multi-pass membrane protein .
功能
alternative products:Comment=Additional isoforms seem to exist,function:Could be involved in cell-cell interactions.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 GPS domain.,similarity:Contains 6 EGF-like domains.,tissue specificity:Wide expression; increased levels in peripheral blood mononuclear cells.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
