产品名称
ELOVL5 Rabbit Polyclonal Antibody
别名
ELOVL5; ELOVL2; Elongation of very long chain fatty acids protein 5; 3-keto acyl-CoA synthase ELOVL5; ELOVL fatty acid elongase 5; ELOVL FA elongase 5; Fatty acid elongase 1; hELO1
蛋白名称
Elongation of very long chain fatty acids protein 5
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=60481
Human Swissprot No.
Q9NYP7
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9NYP7/entry
Mouse Swissprot No.
Q8BHI7
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BHI7
免疫原
The antiserum was produced against synthesized peptide derived from human ELOVL5. AA range:250-299
特异性
ELOVL5 Polyclonal Antibody detects endogenous levels of ELOVL5 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene belongs to the ELO family. It is highly expressed in the adrenal gland and testis, and encodes a multi-pass membrane protein that is localized in the endoplasmic reticulum. This protein is involved in the elongation of long-chain polyunsaturated fatty acids. Mutations in this gene have been associated with spinocerebellar ataxia-38 (SCA38). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014],
组织表达
Ubiquitous. Highly expressed in the adrenal gland and testis. Weakly expressed in prostate, lung and brain. Expressed in the cerebellum.
细胞定位
Endoplasmic reticulum membrane ; Multi-pass membrane protein . Cell projection, dendrite . In Purkinje cells, the protein localizes to the soma and proximal portion of the dendritic tree. .
信号通路
Biosynthesis of unsaturated fatty acids;
功能
function:May be involved in the elongation of long-chain polyunsaturated fatty acids (PUFAs).,similarity:Belongs to the ELO family.,tissue specificity:Highly expressed in the adrenal gland and testis. Weekly expressed in prostate, lung and brain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
