产品名称
ELOVL5 Rabbit Polyclonal Antibody
别名
ELOVL5; ELOVL2; Elongation of very long chain fatty acids protein 5; 3-keto acyl-CoA synthase ELOVL5; ELOVL fatty acid elongase 5; ELOVL FA elongase 5; Fatty acid elongase 1; hELO1
蛋白名称
Elongation of very long chain fatty acids protein 5
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=60481
Human Swissprot No.
Q9NYP7
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9NYP7/entry
Mouse Swissprot No.
Q8BHI7
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BHI7
免疫原
The antiserum was produced against synthesized peptide derived from human ELOVL5. AA range:250-299
特异性
ELOVL5 Polyclonal Antibody detects endogenous levels of ELOVL5 protein.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene belongs to the ELO family. It is highly expressed in the adrenal gland and testis, and encodes a multi-pass membrane protein that is localized in the endoplasmic reticulum. This protein is involved in the elongation of long-chain polyunsaturated fatty acids. Mutations in this gene have been associated with spinocerebellar ataxia-38 (SCA38). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014],
组织表达
Ubiquitous. Highly expressed in the adrenal gland and testis. Weakly expressed in prostate, lung and brain. Expressed in the cerebellum.
细胞定位
Endoplasmic reticulum membrane ; Multi-pass membrane protein . Cell projection, dendrite . In Purkinje cells, the protein localizes to the soma and proximal portion of the dendritic tree. .
信号通路
Biosynthesis of unsaturated fatty acids;
功能
function:May be involved in the elongation of long-chain polyunsaturated fatty acids (PUFAs).,similarity:Belongs to the ELO family.,tissue specificity:Highly expressed in the adrenal gland and testis. Weekly expressed in prostate, lung and brain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.