产品名称
Egr-2 Rabbit Polyclonal Antibody
别名
EGR1; KROX24; ZNF225; Early growth response protein 1; EGR-1; AT225; Nerve growth factor-induced protein A; NGFI-A; Transcription factor ETR103; Transcription factor Zif268; Zinc finger protein 225; Zinc finger protein Krox-24; EGR2; KROX20
蛋白名称
Early growth response protein 2
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1958
Human Swissprot No.
P18146/P11161
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P18146/entry
Mouse Gene ID
13653/13654
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=13653
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=24330
Rat Swissprot No.
P08154/P51774
Rat Swissprot Link
http://www.uniprot.org/uniprot/P08154
免疫原
The antiserum was produced against synthesized peptide derived from human EGR1/2. AA range:371-420
特异性
Egr-2 Polyclonal Antibody detects endogenous levels of Egr-2 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppressor gene. [provided by RefSeq, Dec 2014],
组织表达
Detected in neutrophils (at protein level).
细胞定位
Nucleus . Cytoplasm .
功能
function:Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site). Activates the transcription of target genes whose products are required for mitogenesis and differentiation.,induction:By growth factors.,similarity:Belongs to the EGR C2H2-type zinc-finger protein family.,similarity:Contains 3 C2H2-type zinc fingers.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
