产品名称
EF-Tu Rabbit Polyclonal Antibody
别名
TUFM; Elongation factor Tu; mitochondrial; EF-Tu; P43
蛋白名称
Elongation factor Tu mitochondrial
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7284
Human Swissprot No.
P49411
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P49411/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=233870
Mouse Swissprot No.
Q8BFR5
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BFR5
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=293481
Rat Swissprot Link
http://www.uniprot.org/uniprot/P85834
免疫原
The antiserum was produced against synthesized peptide derived from human TUFM. AA range:301-350
特异性
EF-Tu Polyclonal Antibody detects endogenous levels of EF-Tu protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a protein which participates in protein translation in mitochondria. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency resulting in lactic acidosis and fatal encephalopathy. A pseudogene has been identified on chromosome 17. [provided by RefSeq, Jul 2008],
组织表达
Brain,Cajal-Retzius cell,Heart,Kidney,Liver,Lung,Placenta,P
功能
disease:Defects in TUFM are the cause of combined oxidative phosphorylation deficiency type 4 (COXPD4) [MIM:610678]. COXPD4 is characterized by neonatal lactic acidosis, rapidly progressive encephalopathy, severely decreased mitochondrial protein synthesis, and combined deficiency of mtDNA-related mitochondrial respiratory chain complexes.,function:This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.,similarity:Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
