产品名称
TRP2 DCT (2A10) Mouse Monoclonal Antibody
别名
L-dopachrome tautomerase (DCT) (DT) (EC 5.3.3.12) (L-dopachrome Delta-isomerase) (Tyrosinase-related protein 2) (TRP-2) (TRP2)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.28% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/1638
Human Swissprot No.
P40126
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P40126/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/13190
Mouse Swissprot No.
P29812
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P29812
免疫原
Synthesized peptide derived from human TRP2 DCT
特异性
This antibody detects endogenous levels of TRP2 DCT at Human, Mouse,Rat
稀释度
IHC-p1:50-200 ,WB 1:1000-2000
组织表达
Liver,Lymphnode melanoma metastases,Mammary gland,Melanoma,
细胞定位
Melanosome membrane ; Single-pass type I membrane protein . Melanosome . Proper trafficking to melanosome is regulated by SGSM2, ANKRD27, RAB9A, RAB32 and RAB38. .
功能
catalytic activity:L-dopachrome = 5,6-dihydroxyindole-2-carboxylate.,cofactor:Binds 2 zinc ions per subunit.,function:Involved in regulating eumelanin and phaeomelanin levels.,pathway:Pigment biosynthesis; melanin biosynthesis.,similarity:Belongs to the tyrosinase family.,subunit:Tyrosinase, TYRP1 and TYRP2 may form a multienzyme complex.,
纯化
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
