产品名称
ECP Rabbit Polyclonal Antibody
别名
RNASE3; ECP; RNS3; Eosinophil cationic protein; ECP; Ribonuclease 3; RNase 3
蛋白名称
Eosinophil cationic protein
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6037
Human Swissprot No.
P12724
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P12724/entry
免疫原
The antiserum was produced against synthesized peptide derived from human ECP. AA range:102-151
特异性
ECP Polyclonal Antibody detects endogenous levels of ECP protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene belongs to the pancreatic ribonuclease family, a subset of the ribonuclease A superfamily. The protein exhibits antimicrobial activity against pathogenic bacteria [provided by RefSeq, Oct 2014],
组织表达
Colon,Fetal liver,Peripheral blood granulocyte,
细胞定位
Secreted. Located in the matrix of eosinophil large specific granule, which are released following activation by an immune stimulus.
功能
disease:Induces the neurotoxic effect known as the Gordon phenomenon.,function:Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity.,similarity:Belongs to the pancreatic ribonuclease family.,subcellular location:Matrix of eosinophil's large specific granule.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
