产品名称
KCNT2 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/343450
Human Swissprot No.
Q6UVM3
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q6UVM3/entry
Rat Gene Link
https://www.uniprot.org/uniprot/304827
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q6UVM4
免疫原
Synthesized peptide derived from human KCNT2 AA range: 689-739
特异性
This antibody detects endogenous levels of KCNT2 at Human/Rat
宿主
Polyclonal, Rabbit,IgG
细胞定位
Cell membrane ; Multi-pass membrane protein .
功能
function:Outward rectifying potassium channel. Produces rapidly activating outward rectifier K(+) currents. Activated by high intracellular sodium and chloride levels. Channel activity is inhibited by ATP and by inhalation anesthetics, such as isoflurane (By similarity). Inhibited upon stimulation of G-protein coupled receptors, such as CHRM1 and GRIA1.,PTM:Phosphorylated by protein kinase C. Phosphorylation of the C-terminal domain inhibits channel activity.,similarity:Belongs to the potassium channel family. Calcium-activated subfamily.,similarity:Contains 1 RCK N-terminal domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
