产品名称
DZIP3 Rabbit Polyclonal Antibody
别名
DZIP3; KIAA0675; E3 ubiquitin-protein ligase DZIP3; DAZ-interacting protein 3; RNA-binding ubiquitin ligase of 138 kDa; hRUL138
蛋白名称
E3 ubiquitin-protein ligase DZIP3
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9666
Human Swissprot No.
Q86Y13
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q86Y13/entry
Mouse Swissprot No.
Q7TPV2
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q7TPV2
免疫原
The antiserum was produced against synthesized peptide derived from human DZIP3. AA range:681-730
特异性
DZIP3 Polyclonal Antibody detects endogenous levels of DZIP3 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:E3 Ubiquitin ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Able to specifically bind RNA.,pathway:Protein modification; protein ubiquitination.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Contains 1 RING-type zinc finger.,subunit:Interacts with DAZ proteins.,tissue specificity:Widely expressed at low level. Highly expressed in skeletal muscle, kidney and heart. Expressed at low level in placenta, lung, brain, liver and pancreas.,
组织表达
Widely expressed at low level. Highly expressed in skeletal muscle, kidney and heart. Expressed at low level in placenta, lung, brain, liver and pancreas.
功能
function:E3 Ubiquitin ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Able to specifically bind RNA.,pathway:Protein modification; protein ubiquitination.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Contains 1 RING-type zinc finger.,subunit:Interacts with DAZ proteins.,tissue specificity:Widely expressed at low level. Highly expressed in skeletal muscle, kidney and heart. Expressed at low level in placenta, lung, brain, liver and pancreas.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
