产品名称
Dyrk4 Rabbit Polyclonal Antibody
别名
DYRK4; Dual specificity tyrosine-phosphorylation-regulated kinase 4
蛋白名称
Dual specificity tyrosine-phosphorylation-regulated kinase 4
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8798
Human Swissprot No.
Q9NR20
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9NR20/entry
Mouse Swissprot No.
Q8BI55
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BI55
免疫原
Synthesized peptide derived from Dyrk4 . at AA range: 350-430
特异性
Dyrk4 Polyclonal Antibody detects endogenous levels of Dyrk4 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes an enzyme that belongs to a conserved family of serine/threonine protein kinases. Members of this dual specificity kinase family are thought to function in the regulation of cell differentiation and proliferation, survival, and in development. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Aug 2013],
组织表达
Brain,Kidney,Lung,Testis,
细胞定位
[Isoform 1]: Cytoplasm .; [Isoform 4]: Cytoplasm . Nucleus .
功能
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,function:Possible non-essential role in spermiogenesis.,PTM:Autophosphorylated on tyrosine residues.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.,similarity:Contains 1 protein kinase domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
