产品名称
DRAK2 Rabbit Polyclonal Antibody
别名
STK17B; DRAK2; Serine/threonine-protein kinase 17B; DAP kinase-related apoptosis-inducing protein kinase 2
蛋白名称
Serine/threonine-protein kinase 17B
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9262
Human Swissprot No.
O94768
Human Swissprot Link
http://www.uniprot.org/uniprotkb/O94768/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=98267
Mouse Swissprot No.
Q8BG48
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BG48
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=170904
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q91XS8
免疫原
The antiserum was produced against synthesized peptide derived from human STK17B. AA range:251-300
特异性
DRAK2 Polyclonal Antibody detects endogenous levels of DRAK2 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Acts as a positive regulator of apoptosis.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with CHP causing CHP to translocate from the Golgi to the nucleus.,tissue specificity:Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney.,
组织表达
Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney.
细胞定位
Nucleus . Cell membrane . Endoplasmic reticulum-Golgi intermediate compartment . Colocalizes with STK17B at the plasma membrane. .
功能
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Acts as a positive regulator of apoptosis.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with CHP causing CHP to translocate from the Golgi to the nucleus.,tissue specificity:Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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