BD-PT1389

DOC-1 Rabbit Polyclonal Antibody

CDK2AP1; CDKAP1; DOC1; Cyclin-dependent kinase 2-associated protein 1; CDK2-associated protein 1; Deleted in oral cancer 1; DOC-1; Putative oral cancer suppressor

常规抗体

CDK2AP1

Cyclin-dependent kinase 2-associated protein 1

WB

Human,Mouse

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

8099

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8099

O14519

http://www.uniprot.org/uniprotkb/O14519/entry

13445

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=13445

O35207

http://www.uniprot.org/uniprot/O35207

The antiserum was produced against synthesized peptide derived from human CDKAP1. AA range:51-100

DOC-1 Polyclonal Antibody detects endogenous levels of DOC-1 protein.

WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

20kD

-20°C/1 year

Polyclonal, Rabbit,IgG

cyclin dependent kinase 2 associated protein 1(CDK2AP1) Homo sapiens The protein encoded by this gene is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S-phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation. This gene thus plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012],

Skin,Testis,

nucleus,perinuclear region of cytoplasm,

similarity:Belongs to the CDK2AP family.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.