产品名称
Dlx-5 Rabbit Polyclonal Antibody
别名
DLX5; Homeobox protein DLX-5
蛋白名称
Homeobox protein DLX-5
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1749
Human Swissprot No.
P56178
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P56178/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=13395
Mouse Swissprot No.
P70396
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P70396
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25431
Rat Swissprot Link
http://www.uniprot.org/uniprot/P50575
免疫原
The antiserum was produced against synthesized peptide derived from human DLX5. AA range:91-140
特异性
Dlx-5 Polyclonal Antibody detects endogenous levels of Dlx-5 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. The encoded protein may play a role in bone development and fracture healing. Mutation in this gene, which is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 7, may be associated with split-hand/split-foot malformation. [provided by RefSeq, Jul 2008],
组织表达
Embryo,Lung,Osteoblast,Placenta,
功能
developmental stage:First expressed in embryos at 8.5-9 days in facial and branchial arch mesenchyme, otic vesicles and frontonasal ectoderm around olfactory placodes, a day later expression is seen in the developing forebrain in primordia of the ganglionic eminence and ventral diencephalic regions. In day 12.5 embryos, expressed in the brain and bones, and also in all skeletal structures of midgestation embryos after the first cartilage formation. Expression remains unaltered in both brain and skeleton in day 15 embryos and slowly decreases in day 17 embryos.,similarity:Belongs to the distal-less homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,subunit:Interacts with G22P1 (Ku70).,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
