产品名称
DHODH Rabbit Polyclonal Antibody
别名
DHODH; Dihydroorotate dehydrogenase; quinone); mitochondrial; DHOdehase; Dihydroorotate oxidase
蛋白名称
Dihydroorotate dehydrogenase
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1723
Human Swissprot No.
Q02127
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q02127/entry
Mouse Swissprot No.
O35435
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O35435
免疫原
The antiserum was produced against synthesized peptide derived from human DHODH. AA range:211-260
特异性
DHODH Polyclonal Antibody detects endogenous levels of DHODH protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene catalyzes the fourth enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate to orotate, in de novo pyrimidine biosynthesis. This protein is a mitochondrial protein located on the outer surface of the inner mitochondrial membrane. [provided by RefSeq, Jul 2008],
细胞定位
Mitochondrion inner membrane ; Single-pass membrane protein .
信号通路
Pyrimidine metabolism;
功能
catalytic activity:(S)-dihydroorotate + O(2) = orotate + H(2)O(2).,cofactor:Binds 1 FAD per subunit.,pathway:Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from HCO(3)(-): step 4/6.,similarity:Belongs to the dihydroorotate dehydrogenase family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
