产品名称
DHA Kinase Rabbit Polyclonal Antibody
别名
DAK; Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase; cyclizing
蛋白名称
Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=26007
Human Swissprot No.
Q3LXA3
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q3LXA3/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=225913
Mouse Swissprot No.
Q8VC30
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8VC30
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=361730
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q4KLZ6
免疫原
The antiserum was produced against synthesized peptide derived from human DAK. AA range:91-140
特异性
DHA Kinase Polyclonal Antibody detects endogenous levels of DHA Kinase protein.
稀释度
WB 1:200 - 1:1000. ELISA: 1:20000.. IF 1:20-50
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene is a member of the family of dihydroxyacetone kinases, which have a protein structure distinct from other kinases. The product of this gene phosphorylates dihydroxyacetone, and also catalyzes the formation of riboflavin 4',5'-phosphate (aka cyclin FMN) from FAD. Several alternatively spliced transcript variants have been identified, but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008],
组织表达
Detected in erythrocytes (at protein level).
细胞定位
nucleus,cytosol,extracellular exosome,
信号通路
Glycerolipid metabolism;RIG-I-like receptor;
功能
catalytic activity:ATP + glycerone = ADP + glycerone phosphate.,catalytic activity:FAD = AMP + riboflavin cyclic-4',5'-phosphate.,cofactor:Magnesium.,cofactor:Manganese or cobalt; for FAD-AMP lyase activity.,enzyme regulation:Each activity is inhibited by the substrate(s) of the other.,function:Catalyzes both the phosphorylation of dihydroxyacetone and the splitting of ribonucleoside diphosphate-X compounds among which FAD is the best substrate.,similarity:Belongs to the dihydroxyacetone kinase (DAK) family.,similarity:Contains 1 DAK1 (dihydroxyacetone kinase subunit 1) domain.,similarity:Contains 1 DAK2 (dihydroxyacetone kinase subunit 2) domain.,subunit:Homodimer.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
