产品名称
KINH Rabbit Polyclonal Antibody
别名
Kinesin-1 heavy chain (Conventional kinesin heavy chain) (Ubiquitous kinesin heavy chain) (UKHC)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.266% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/3799
Human Swissprot No.
P33176
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P33176/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/16573
Mouse Swissprot No.
Q61768
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q61768
Rat Gene Link
https://www.uniprot.org/uniprot/117550
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q2PQA9
免疫原
Synthesized peptide derived from human KINH AA range: 64-114
特异性
This antibody detects endogenous levels of KINH at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
组织表达
Muscle,Placenta,Uterus,
细胞定位
Cytoplasm, cytoskeleton . Cytolytic granule membrane . Lysosome membrane ; Peripheral membrane protein ; Cytoplasmic side . Uniformly distributed between soma and neurites in hippocampal neurons. .
功能
domain:Composed of three structural domains: a large globular N-terminal domain which is responsible for the motor activity of kinesin (it hydrolyzes ATP and binds microtubule), a central alpha-helical coiled coil domain that mediates the heavy chain dimerization; and a small globular C-terminal domain which interacts with other proteins (such as the kinesin light chains), vesicles and membranous organelles.,function:Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes.,similarity:Belongs to the kinesin-like protein family.,similarity:Belongs to the kinesin-like protein family. Kinesin subfamily.,similarity:Contains 1 kinesin-motor domain.,subcellular location:Uniformly distributed between soma and neurites in hippocampal neurons.,subunit:Oligomer composed of two heavy chains and two light chains. Interacts with GRIP1 (By similarity). Interacts with SYBU. Interacts with JAKMIP1.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
