产品名称
DECR2 Rabbit Polyclonal Antibody
别名
DECR2; PDCR; Peroxisomal 2; 4-dienoyl-CoA reductase; pDCR; 2,4-dienoyl-CoA reductase 2
蛋白名称
Peroxisomal 2,4-dienoyl-CoA reductase
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=26063
Human Swissprot No.
Q9NUI1
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9NUI1/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=26378
Mouse Swissprot No.
Q9WV68
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9WV68
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=64461
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q9Z2M4
免疫原
The antiserum was produced against synthesized peptide derived from human DECR2. AA range:217-266
特异性
DECR2 Polyclonal Antibody detects endogenous levels of DECR2 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
catalytic activity:Trans-2,3-didehydroacyl-CoA + NADP(+) = trans,trans-2,3,4,5-tetradehydroacyl-CoA + NADPH.,function:Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19-docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid.,similarity:Belongs to the short-chain dehydrogenases/reductases (SDR) family.,similarity:Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily.,
组织表达
Brain,Epithelium,Lung,Testis,
功能
catalytic activity:Trans-2,3-didehydroacyl-CoA + NADP(+) = trans,trans-2,3,4,5-tetradehydroacyl-CoA + NADPH.,function:Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19-docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid.,similarity:Belongs to the short-chain dehydrogenases/reductases (SDR) family.,similarity:Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
