产品名称
DDX54 Rabbit Polyclonal Antibody
别名
DDX54; ATP-dependent RNA helicase DDX54; ATP-dependent RNA helicase DP97; DEAD box RNA helicase 97 kDa; DEAD box protein 54
蛋白名称
ATP-dependent RNA helicase DDX54
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=79039
Human Swissprot No.
Q8TDD1
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q8TDD1/entry
Mouse Swissprot No.
Q8K4L0
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8K4L0
免疫原
Synthesized peptide derived from DDX54 . at AA range: 570-650
特异性
DDX54 Polyclonal Antibody detects endogenous levels of DDX54 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The nucleolar protein encoded by this gene interacts in a hormone-dependent manner with nuclear receptors, and represses their transcriptional activity. Alternative splice variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
组织表达
Expressed in the fallopian tube, cervix and uterus. Also expressed in the brain.
细胞定位
Nucleus, nucleolus .
功能
caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:Has RNA-dependent ATPase activity. Represses the transcriptional activity of nuclear receptors.,similarity:Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.,similarity:Contains 1 helicase ATP-binding domain.,similarity:Contains 1 helicase C-terminal domain.,subunit:Interacts in a hormone-dependent manner with nuclear receptors.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
