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CYP4Z1 Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT1239
产品名称
CYP4Z1 Rabbit Polyclonal Antibody
别名
CYP4Z1; Cytochrome P450 4Z1; CYPIVZ1
类别
常规抗体
基因名称
CYP4Z1
蛋白名称
Cytochrome P450 4Z1
推荐应用
WB
反应种属
Human,Rat,Mouse
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
199974
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=199974
Human Swissprot No.
Q86W10
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q86W10/entry
免疫原
The antiserum was produced against synthesized peptide derived from human Cytochrome P450 4Z1. AA range:71-120
特异性
CYP4Z1 Polyclonal Antibody detects endogenous levels of CYP4Z1 protein.
稀释度
WB 1:500-2000 IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
参考分子量
59kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
CYP4Z1 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP4Z1 is part of a cluster of cytochrome P450 genes on chromosome 1p33.
组织表达
Preferentially detected in breast carcinoma tissue and mammary gland, whereas only marginal expression is found in all other tested tissues.
细胞定位
Endoplasmic reticulum membrane ; Single-pass type II membrane protein . Microsome membrane ; Single-pass type II membrane protein .
功能
oxidation reduction,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunofluorescence analysis of HUVEC cells, using Cytochrome P450 4Z1 Antibody. The picture on the right is blocked with the synthesized peptide.

Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue, using Cytochrome P450 4Z1 Antibody. The picture on the right is blocked with the synthesized peptide.

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