产品名称
CYP4F11 Rabbit Polyclonal Antibody
别名
CYP4F11; Cytochrome P450 4F11; CYPIVF11
蛋白名称
Cytochrome P450 4F11
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=57834
Human Swissprot No.
Q9HBI6
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9HBI6/entry
免疫原
The antiserum was produced against synthesized peptide derived from human Cytochrome P450 4F11. AA range:341-390
特异性
CYP4F11 Polyclonal Antibody detects endogenous levels of CYP4F11 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
cytochrome P450 family 4 subfamily F member 11(CYP4F11) Homo sapiens This gene, CYP4F11, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F2, is approximately 16 kb away. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008],
组织表达
Expressed mainly in human liver, followed by kidney, heart, and skeletal muscle.
细胞定位
Endoplasmic reticulum membrane ; Single-pass membrane protein . Microsome membrane ; Single-pass membrane protein .
功能
catalytic activity:RH + reduced flavoprotein + O(2) = ROH + oxidized flavoprotein + H(2)O.,cofactor:Heme group.,similarity:Belongs to the cytochrome P450 family.,tissue specificity:Expressed mainly in human liver, followed by kidney, heart, and skeletal muscle.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
