产品名称
CYP2U1 Rabbit Polyclonal Antibody
别名
CYP2U1; Cytochrome P450 2U1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=113612
Human Swissprot No.
Q7Z449
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q7Z449/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=71519
Mouse Swissprot No.
Q9CX98
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9CX98
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=310848
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q4V8D1
免疫原
The antiserum was produced against synthesized peptide derived from human Cytochrome P450 2U1. AA range:281-330
特异性
CYP2U1 Polyclonal Antibody detects endogenous levels of CYP2U1 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a hydroxylase that metabolizes arachidonic acid, docosahexaenoic acid, and other long chain fatty acids. [provided by RefSeq, Jul 2008],
组织表达
Widely expressed with stronger expression in thymus, heart and cerebellum.
细胞定位
Endoplasmic reticulum membrane ; Multi-pass membrane protein . Microsome membrane ; Multi-pass membrane protein . Mitochondrion inner membrane ; Multi-pass membrane protein .
信号通路
Arachidonic acid metabolism;
功能
catalytic activity:RH + reduced flavoprotein + O(2) = ROH + oxidized flavoprotein + H(2)O.,cofactor:Heme group.,developmental stage:Expressed in fetal thymus.,function:Catalyzes the hydroxylation of arachidonic acid, docosahexaenoic acid and other long chain fatty acids. May modulate the arachidonic acid signaling pathway and play a role in other fatty acid signaling processes.,similarity:Belongs to the cytochrome P450 family.,tissue specificity:Widely expressed with stronger expression in thymus, heart and cerebellum.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
