产品名称
CYP26C1 Rabbit Polyclonal Antibody
别名
CYP26C1; Cytochrome P450 26C1
蛋白名称
Cytochrome P450 26C1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=340665
Human Swissprot No.
Q6V0L0
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q6V0L0/entry
免疫原
Synthesized peptide derived from the Internal region of human CYP26C1.
特异性
CYP26C1 Polyclonal Antibody detects endogenous levels of CYP26C1 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
cytochrome P450 family 26 subfamily C member 1(CYP26C1) Homo sapiens This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is involved in the catabolism of all-trans- and 9-cis-retinoic acid, and thus contributes to the regulation of retinoic acid levels in cells and tissues. This gene is adjacent to a related gene on chromosome 10q23.33. [provided by RefSeq, Jul 2008],
组织表达
Detected in most tissues at very low level.
细胞定位
Membrane ; Single-pass membrane protein .
功能
cofactor:Heme group.,function:Plays a role in retinoic acid metabolism. Acts on retinoids, including all-trans-retinoic acid (RA) and its stereoisomer 9-cis-RA (preferred substrate).,induction:By retinoic acid.,similarity:Belongs to the cytochrome P450 family.,tissue specificity:Detected in most tissues at very low level.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
