产品名称
CYP20A1 Rabbit Polyclonal Antibody
别名
CYP20A1; Cytochrome P450 20A1
蛋白名称
Cytochrome P450 20A1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=57404
Human Swissprot No.
Q6UW02
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q6UW02/entry
Mouse Swissprot No.
Q8BKE6
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BKE6
免疫原
The antiserum was produced against synthesized peptide derived from human Cytochrome P450 20A1. AA range:191-240
特异性
CYP20A1 Polyclonal Antibody detects endogenous levels of CYP20A1 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
cytochrome P450 family 20 subfamily A member 1(CYP20A1) Homo sapiens This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein lacks one amino acid of the conserved heme binding site. It also lacks the conserved I-helix motif AGX(D,E)T, suggesting that its substrate may carry its own oxygen. [provided by RefSeq, Jul 2008],
组织表达
Blood,Lung,Pheochromocytoma,Placenta,Stomach,
细胞定位
Membrane ; Single-pass membrane protein .
功能
catalytic activity:RH + reduced flavoprotein + O(2) = ROH + oxidized flavoprotein + H(2)O.,cofactor:Heme group.,similarity:Belongs to the cytochrome P450 family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.