产品名称
Cyclophilin F Rabbit Polyclonal Antibody
别名
PPIF; CYP3; Peptidyl-prolyl cis-trans isomerase F; mitochondrial; PPIase F; Cyclophilin F; Rotamase F
蛋白名称
Peptidyl-prolyl cis-trans isomerase F mitochondrial
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10105
Human Swissprot No.
P30405
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P30405/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=105675
Mouse Swissprot No.
Q99KR7
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q99KR7
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=282819
Rat Swissprot Link
http://www.uniprot.org/uniprot/P29117
免疫原
The antiserum was produced against synthesized peptide derived from human PPIF. AA range:86-135
特异性
Cyclophilin F Polyclonal Antibody detects endogenous levels of Cyclophilin F protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death. [provided by RefSeq, Jul 2008],
组织表达
Blood,Cord blood,Ovary,
细胞定位
Mitochondrion matrix .
功能
catalytic activity:Peptidylproline (omega=180) = peptidylproline (omega=0).,function:PPIases accelerate the folding of proteins.,function:PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.,similarity:Belongs to the cyclophilin-type PPIase family.,similarity:Contains 1 PPIase cyclophilin-type domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
.jpg)
