产品名称
SYAC Rabbit Polyclonal Antibody
别名
Alanine--tRNA ligase, cytoplasmic (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS) (Renal carcinoma antigen NY-REN-42)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.278% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/16
Human Swissprot No.
P49588
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P49588/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/234734
Mouse Swissprot No.
Q8BGQ7
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BGQ7
Rat Gene Link
https://www.uniprot.org/uniprot/292023
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P50475
免疫原
Synthesized peptide derived from human SYAC AA range: 504-554
特异性
This antibody detects endogenous levels of SYAC at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity witht the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure. [provided by RefSeq, Jul 2008],
组织表达
Epithelium,Liver,Osteosarcoma,Placenta,Renal cell carcinoma,
功能
catalytic activity:ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala).,similarity:Belongs to the class-II aminoacyl-tRNA synthetase family.,subunit:Monomer.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
