产品名称
CYB5R1 Rabbit Polyclonal Antibody
别名
CYB5R1; NQO3A2; NADH-cytochrome b5 reductase 1; b5R.1; Humb5R2; NAD(P)H:quinone oxidoreductase type 3 polypeptide A2
蛋白名称
NADH-cytochrome b5 reductase 1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=51706
Human Swissprot No.
Q9UHQ9
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9UHQ9/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=72017
Mouse Swissprot No.
Q9DB73
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9DB73
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=304805
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q5EB81
免疫原
The antiserum was produced against synthesized peptide derived from human CYB5R1. AA range:9-58
特异性
CYB5R1 Polyclonal Antibody detects endogenous levels of CYB5R1 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
catalytic activity:NADH + 2 ferricytochrome b5 = NAD(+) + H(+) + 2 ferrocytochrome b5.,cofactor:FAD.,function:NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction.,similarity:Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.,similarity:Contains 1 FAD-binding FR-type domain.,tissue specificity:Widely expressed.,
细胞定位
Membrane ; Single-pass membrane protein .
信号通路
Amino sugar and nucleotide sugar metabolism;
功能
catalytic activity:NADH + 2 ferricytochrome b5 = NAD(+) + H(+) + 2 ferrocytochrome b5.,cofactor:FAD.,function:NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction.,similarity:Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.,similarity:Contains 1 FAD-binding FR-type domain.,tissue specificity:Widely expressed.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.