BD-PT1150-CTDSP1 Rabbit Polyclonal Antibody-现货抗体产品库武汉枢密脑科学技术有限公司

CTDSP1 Rabbit Polyclonal Antibody

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产品基本信息

产品货号

BD-PT1150

产品名称

CTDSP1 Rabbit Polyclonal Antibody

别名

CTDSP1; NIF3; NLIIF; SCP1; Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1; Nuclear LIM interactor-interacting factor 3; NLI-IF; NLI-interacting factor 3; Small C-terminal domain phosphatase 1; SCP1; Small CTD ph

类别

常规抗体

基因名称

CTDSP1

蛋白名称

Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

推荐应用

反应种属

Human,Mouse,Rat

浓度

1 mg/ml

存储缓冲液

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Human Gene ID

58190

Human Gene Link

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=58190

Human Swissprot No.

Q9GZU7

Human Swissprot Link

http://www.uniprot.org/uniprotkb/Q9GZU7/entry

Mouse Gene ID

227292

Mouse Gene Link

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=227292

Mouse Swissprot No.

P58466

Mouse Swissprot Link

http://www.uniprot.org/uniprot/P58466

免疫原

The antiserum was produced against synthesized peptide derived from human CTDSP1. AA range:1-50

特异性

CTDSP1 Polyclonal Antibody detects endogenous levels of CTDSP1 protein.

稀释度

WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

预测分子量

30kD

运输及保存条件

-20°C/1 year

宿主

Polyclonal, Rabbit,IgG

背景介绍

CTD small phosphatase 1(CTDSP1) Homo sapiens This gene encodes a member of the small C-terminal domain phosphatase (SCP) family of nuclear phosphatases. These proteins play a role in transcriptional regulation through specific dephosphorylation of phosphoserine 5 within tandem heptapeptide repeats of the C-terminal domain of RNA polymerase II. The encoded protein plays a role in neuronal gene silencing in non-neuronal cells, and may also inhibit osteoblast differentiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011],

组织表达

Expression is restricted to non-neuronal tissues. Highest expression in skeletal muscle, spleen, lung and placenta.

细胞定位

Nucleus . Colocalizes with RNA polymerase II.

功能

catalytic activity:A phosphoprotein + H(2)O = a protein + phosphate.,similarity:Contains 1 FCP1 homology domain.,subunit:May interact with LDB1 .,tissue specificity:Ubiquitously expressed, with highest expression in spleen, lung and placenta.,

期货

现货

纯化

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using CTDSP1 Antibody. The picture on the right is blocked with the synthesized peptide.

Western blot analysis of lysates from HeLa and HUVEC cells, using CTDSP1 Antibody. The lane on the right is blocked with the synthesized peptide.

Western blot analysis of the lysates from HepG2 cells using CTDSP1 antibody.

Western Blot analysis of various cells using CTDSP1 Polyclonal Antibody diluted at 1：1000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit （SC-003,Inventbiotech,MN,USA）.

Western blot analysis of mouse-brain HELA KB SH-SY5Y 293T 3T3 lysis using CTDSP1 antibody. Antibody was diluted at 1:1000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit （SC-003,Inventbiotech,MN,USA）.