产品名称
GMIP Rabbit Polyclonal Antibody
别名
GEM-interacting protein (GMIP)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.282% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/51291
Human Swissprot No.
Q9P107
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9P107/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/78816
Mouse Swissprot No.
Q6PGG2
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q6PGG2
免疫原
Synthesized peptide derived from human GMIP AA range: 421-471
特异性
This antibody detects endogenous levels of GMIP at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the ARHGAP family of Rho/Rac/Cdc42-like GTPase activating proteins. The encoded protein interacts with the Ras-related protein Gem through its N-terminal domain. Separately, it interacts with RhoA through a RhoGAP domain, and stimulates RhoA-dependent GTPase activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014],
组织表达
Brain,Leukemia,Platelet,
细胞定位
intracellular,cytosol,
功能
function:Stimulates, in vitro and in vivo, the GTPase activity of RhoA.,similarity:Contains 1 phorbol-ester/DAG-type zinc finger.,similarity:Contains 1 Rho-GAP domain.,subunit:Interacts with GEM through its N-terminal.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
