BD-PT1091

CPTI-M Rabbit Polyclonal Antibody

CPT1B; KIAA1670; Carnitine O-palmitoyltransferase 1; muscle isoform; CPT1-M; Carnitine O-palmitoyltransferase I, muscle isoform; CPT I; CPTI-M; Carnitine palmitoyltransferase 1B; Carnitine palmitoyltransferase I-like protein

常规抗体

CPT1B

Carnitine O-palmitoyltransferase 1 muscle isoform

WB

Human,Rat,Mouse

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

1120/1375

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1120

Q92523

http://www.uniprot.org/uniprotkb/Q92523/entry

Q924X2

http://www.uniprot.org/uniprot/Q924X2

The antiserum was produced against synthesized peptide derived from human CPT1B. AA range:401-450

CPTI-M Polyclonal Antibody detects endogenous levels of CPTI-M protein.

WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

88kD

-20°C/1 year

Polyclonal, Rabbit,IgG

The protein encoded by this gene, a member of the carnitine/choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene. [provided by RefSeq, Jun 2009],

Strong expression in heart and skeletal muscle. No expression in liver and kidney.

Mitochondrion outer membrane ; Multi-pass membrane protein .

Fatty acid metabolism;Glycerophospholipid metabolism;PPAR;Adipocytokine;

catalytic activity:ATP + choline = ADP + O-phosphocholine.,catalytic activity:ATP + ethanolamine = ADP + O-phosphoethanolamine.,catalytic activity:Palmitoyl-CoA + L-carnitine = CoA + L-palmitoylcarnitine.,miscellaneous:This protein is produced by a bicistronic gene which also produces the CHKB protein from a non-overlapping reading frame.,miscellaneous:This protein is produced by a bicistronic gene which also produces the CPT1B protein from a non-overlapping reading frame.,pathway:Lipid metabolism; fatty acid beta-oxidation.,similarity:Belongs to the carnitine/choline acetyltransferase family.,similarity:Belongs to the choline/ethanolamine kinase family.,tissue specificity:Strong expression in heart and skeletal muscle. No expression in liver and kidney.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.